Synthetic Organic Chemistry OpenCourseWare: A Free Graduate Level Course by MIT on Synthetic Organic Chemistry

Published Feb 12, 2009

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The Massachusetts Institute of Technology's (MIT) free 'Synthetic Organic Chemistry II' OpenCourseWare covers methods of synthesizing complex organic molecules. Students taking this graduate course must have taken the first course in the synthetic organic chemistry sequence. This course is designed for students pursuing a Ph.D. in Chemistry.

Synthetic Organic Chemistry II: Course Specifics

Degree Level Free Audio Video Downloads
Graduate Yes No No Yes

Lectures/Notes Study Materials Tests/Quizzes
Yes Yes No

Synthetic Organic Chemistry II: Course Description

This OpenCourseWare in synthesizing large, complex molecules in advanced organic chemistry is offered by the Department of Chemistry at MIT in Cambridge, MA. The course begins with stereocontrolled synthesis. Students learn to control the thermodynamic properties of these molecules through destabilizing non-bonded repulsion, stabilizing non-covalent interactions and stereoelectronic effects. The course follows up with stereocontrolled alkylation, covering intrinsic stereochemistry, substrate control reagent control strategies and catalytic methods. Students also study stereocontrolled aldol reactions, stereocontrolled carbonyl and alkene reduction, stereocontrolled dihydroxylation and stereocontrolled epoxidation. The lecture notes are augmented with problem sets. Chemistry professor Dr. Rick Danheiser teaches this course.

This OpenCourseWare includes a required readings list, lecture notes, syllabus and problem sets. Those interested in this free course should visit the Synthetic Organic Chemistry II course page.

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